AntidiabeticEffects Helping to prevent diabetes. It also helps to treat insulin resistance. Many studies have a shown a connection between chronic inflammation and insulin resistance. When inflammation is reduced, the immune system and cardiovascular system function better. A lack of inflammation can also improve cell growth and improve sugar metabolism. It is also helpful to treat neuropathy. CBD speeds healing for skin complications. All while working to prevent obesity.
AntiepilepticandAnticonvulsant Effects Studies in the U.S. of Epidiolex (a plant-based CBD formulation) have been ongoing for a number of years. Data from these studies has helped provide evidence that led to the FDA approval of this product on June 25, 2018. Epidiolex is a purified (98% oil-based) CBD extract from the cannabis plant. For information on clinical trials click here.
Antispastic and MuscleRelaxant Effects CBD is a muscle relaxant and has the ability to decrease muscle spasms and reduce spasticity – a condition in which muscles are continuously contracted. Anandamide, when it stimulates the CB1 receptors, produces antispasmodic effects. CBD produces antispasmodic and antispastic effects by enhancing anandamide levels.
CBD has the potential to reduce spasms and spasticity in multiple sclerosis, spinal cord injury and spasticity and Parkinson’s Disease. Ongoing studies on THC and CBD are working towards learning their effects on spasticity associated with cerebral palsy, dystonia, and neurodegenerative diseases.
Anti-inflammatoryEffects Inflammation in the body can be a big problem for you the older you get. In response, the body activates a system to increase cortisol (an anti-inflammatory hormone). The problem, though, is that a continuous activation of these systems can lead to blood sugar imbalance and diabetes, immune system suppression, weight gain and obesity, gastrointestinal problems, cardiovascular disease, and even fertility problems. Moreover, although you’d expect that an immune system continuously operating on a higher level would be more effective, it’s actually detrimental. Instead, the low-grade continuous activation actually hinders the immune system’s ability to respond effectively to injuries or infection.
Antianxietyand Antidepressant Effects How exactly does it work to control anxiety? CBD is a 5-HT1A (serotonin receptor) agonist, which is a serotonin receptor. It is often targeted by SSRIs (selective serotonin reuptake inhibitors). SSRI is a common medication group used to treat anxiety and anxiety-related disorders. This medication helps to block the absorption of serotonin in the brain, increasing the brain’s ability to transport even more signals, reduce anxiety, and boost overall mood.
In similar ways CBD can boost signals to serotonin receptors, increasing the transmission of 5-HT1A and possibly affecting mood faster than traditional SSRIs. Also without the side effects and unpleasantries that are associated with the medications typically given to treat depression.
NeuroprotectiveEffects CBD has also been shown to have neuroprotective properties in cell cultures as well as in animal models of several neurodegenerative diseases, including Alzheimer’s, strokes,multiple sclerosis, Parkinson’s disease, neurodegeneration caused by alcohol abuse. Alzheimer’s disease is a very common condition that occurs due to the degeneration of neurons. CBD has shown a positive impact in treating such disease. CBD for Alzheimer’s can be used to alleviate the symptoms of the Alzheimer’s as well.
AntianalgesicEffects CBD reduces pain. Endocannabinoids circulate via the bloodstream and cause their effect by binding to our cannabinoid receptors. Currently, we know about two cannabinoid receptors: CB1 and CB2. The ones which are important with regard to nerve pain are our CB1 receptors. These are found in nerve endings and the brain, and have been linked to the origin of the pain sensation. CBD works on the body by reducing the metabolic breakdown of endocannabinoids, which our bodies make naturally. By slowing this breakdown process, CBD indirectly increases the amount and activity of endocannabinoids at the CB1 and CB2 receptors. This in turn causes the pain sensation to alleviate, and sometimes even reverse.
Antiemetic Effects CBD can reduce nausea and vomiting in patients with medical diseases and also in cancer patients seeking chemotherapy. CBD stimulates the dorsal raphe nucleus to produce its anti-nausea and anti-vomiting effects. By working naturally with your body’s endocannabinoid system to keep anandamide in our body longer it helps to produce antiemetic effects.
Antidiarrheal Effects Acetylcholine is released by the neurons in the gut. It is a chemical compound that facilitates the contractions of the intestinal tract. When gastrointestinal problems cause diarrhea and abdominal cramping, drugs are used to block the effects of acetylcholine. Though the side effects of these drugs are constipation, dry mouth, and problems with urination. CBD has demonstrated the ability to stop acetylcholine and reduce intestinal motility.
Antipsychotic Effects Anandamide has antipsychotic effects. Studies measuring anandamide levels and its correlation to psychotic symptoms show that people with psychosis had lower anandamide levels. While CBD allows anandamide to stay in our system longer while producing therapeutic effects. CBD can help conditions like schizophrenia and bipolar disorder.
AntioxidantEffects CBD works by interacting with the endocannabinoid system. Though it can be most significantly attributed to the control of cellular regrowth and neurocellular health. CBD helps the body by interacting with the CB1 and CB2 receptors, which then encourage the body to heal itself through its regular processes. With regard to antioxidant effects, the CB2 receptor is responsible for healthy regulation of neurological cells – the cells that make up the neurons in your brain.
Antitumor and Anticancer Effects CBD has shown much potential for cancer treatment. CBD has the ability to prevent the formation of blood vessels. Stopping the cancer from growing and spreading. CBD induces cancer cell death. Chemotherapy kills not just the cancer cells but healthy ones as well. CBD does not harm the healthy and non-cancerous cells. It only induces apoptosis of the abnormal and cancerous cells.